2-Chlorothiophene-5-carboxylic acid is a kind of pharmaceutical intermediate, which can be used to prepare 5-chlorothiophene-2-formyl chloride, the intermediate of rivaroxaban. RivaChemicalbookroxaban, a new oral anticoagulant drug, has a long effect through oral absorption. It is used to prevent and treat venous thrombosis, with a wide treatment range and no need for routine coagulation function monitoring