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对氨基苯砷酸

英文名: arsanilic acid

CAS: 98-50-0      分子式: C6H8AsNO3

分子量: 217.05400

别名: 对氨基苯胂酸; 4-氨基苯胂酸;


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描述

Arsanilic acid, also known as aminophenyl arsenic acid or aminophenyl arsonic acid, is an organoarsenic compound, an amino derivative of phenylarsonic acid whose amine group is in the 4-position. A crystalline powder introduced medically in the late 19th century as Atoxyl, its sodium salt was used by injection in the early 20th century as the first organic arsenical drug, but it was soon found prohibitively toxic for human use. Arsanilic acid saw long use as a veterinary feed additive promoting growth and to prevent or treat dysentery in poultry and swine. In 2013, its approval by US government as an animal drug was voluntarily withdrawn by its sponsors. Still sometimes used in laboratories, arsanilic acid's legacy is principally through its influence on Paul Ehrlich in launching the chemotherapeutic approach to treating infectious diseases of humans.

基本信息
英文名:
arsanilic acid
CAS号.:
98-50-0
别名:
p-Arsanilic acid; (4-aminophenyl)arsonic acid; Arsonic acid, (4-aminophenyl)-;
分子式:
C6H8AsNO3
分子量:
217.05400
PSA:
83.55000
LogP:
-0.58900
物化属性
外观:
密度:
white crystalline powder
熔点:
≥300 °C(lit.)
沸点:
528.5ºC at 760 mmHg
闪点:
273.4ºC
储存条件:
安全信息
海关编码:
29310095
WGK Germany:
3
危险类别码:
R23/25; R50/53
安全说明:
S20/21-S28-S45-S60-S61-S28A
危险品标志:
T; N
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