英文名: Naproxen
CAS: 22204-53-1 分子式: C14H14O3
分子量: 230.25900
别名: (S)-(+)-6-甲氧基-alpha-甲基-2-萘乙酸; 消炎宁; 氧萘丙酸; (+)-2-甲基-6-甲氧基-2-萘乙酸; (+)α-甲基-6-甲氧基-2-萘乙酸; (S)-(+)-2-(6-甲氧基-2-萘基)丙酸; (S)-(+)-6-甲氧基-α-甲基-2-萘乙酸;
Naproxen (brand names: Aleve, Naprosyn, and many others) is a nonsteroidal anti-inflammatory drug (NSAID) of the propionic acid class (the same class as ibuprofen) that relieves pain, fever, swelling, and stiffness.:665,673 It is a nonselective COX inhibitor, usually sold as the sodium salt. It is the preferred NSAID for long-term use in people with a high risk of cardiovascular complications (for example, heart attacks or strokes),:665 due to its relatively low risk of such complications. Naproxen poses an intermediate risk of stomach ulcers compared to ibuprofen, which is low-risk, and indometacin, which is high-risk. To reduce stomach ulceration risk, it is often combined with a proton-pump inhibitor (a medication that reduces stomach acid production) during long-term treatment of those with pre-existing stomach ulcers or a history of developing stomach ulcers while on NSAIDs.:665,673