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香草壬酰胺

英文名: nonivamide

CAS: 2444-46-4      分子式: C17H27NO3

分子量: 293.40100

别名: 合成辣椒素; N-壬酸香草酰胺; N-(4-羟基-3-甲氧基苄基)壬酰胺; 壬酸香草酰胺; 壬酰-4-羟-3-甲氧基苄胺; 洛里维德; 羟基甲氧基苄基壬酰胺;


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描述

Nonivamide, also called pelargonic acid vanillylamide or PAVA, is an organic compound and a capsaicinoid. It is an amide of pelargonic acid (n-nonanoic acid) and vanillyl amine. It is present in chili peppers, but is commonly manufactured synthetically. It is more heat-stable than capsaicin. Ointment sold under trade name Finalgon is used to relieve arthritis and muscle pain. A small drop of the ointment applied on the skin is absorbed quickly causing warm to burning sensation and pain relief for several hours.[weaselwords]; Nonivamide is used as a food additive to add pungency to seasonings, flavorings, and spice blends. It is also used in the confectionery industry to create a hot sensation, and in the pharmaceutical industry in some formulations as a cheaper alternative to capsaicin. Like capsaicin, it can deter mammals (but not birds or insects) from consuming plants or seeds (e.g. squirrels and bird feeder seeds). This is consistent with nonivamide's role as a TRPV1 ion channel agonist. Mammalian TRPV1 is activated by heat and capsaicin, but the avian form is insensitive to capsaicin. Nonivamide is used (under the name PAVA) as the payload in "less-lethal munitions" such as the Fabrique Nationale Herstal FN 303 or as the active ingredient in most pepper sprays - in both applications, the idea is to temporarily incapacitate people so that they can either be detained prior to arrest or deterred from acts of violence toward law-enforcement personnel or third parties (such as rioting or other group violence).

基本信息
英文名:
nonivamide
CAS号.:
2444-46-4
别名:
N-vanillyl-nonanamide; (N-(4-Hydroxy-3-methoxybenzyl)nonanamide; Nonivamide; Pseudocapsaicin; Capsaicin (Synthetic); N-VANILLYLNONANOAMIDE; N-Nonylvanylamide; NonvaMide; Capsaicin std.; nonanoic acid vanillylamide; N-(4-Hydroxy-3-methoxybenzyl)nonanamide; Capsaicinoid; N-Pelargonic Acid Vanillylamide; Capsaicin synthetic; Pelargonic acid vanillylamide; NONYLVANYLAMIDE; N-Pelargonylvanillylamide; N-Vanillylnonanamide; nonylic acid vanillylamide; PAVA; NON-4-ENE; N-Vanillylpelargonamide;
分子式:
C17H27NO3
分子量:
293.40100
PSA:
58.56000
LogP:
4.15850
物化属性
外观:
white to brown powder
密度:
1,1 g/cm3
熔点:
54°C
沸点:
492.7ºC at 760 mmHg
闪点:
190°C
储存条件:
2-8ºC
安全信息
信号词:
Warning
海关编码:
2924299090
WGK Germany:
3
危险类别码:
R25; R36/37/38
安全说明:
S26-S45
危险品标志:
T
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